The St Regis Osaka puts you just a 5-minute drive from Dotonbori and Tsutenkaku Tower. Guests can visit the spa to be pampered with massages, body wraps, or facials, and Rue d'OR, one of 3 restaurants, serves French cuisine and is open for breakfast, lunch, and dinner. Other highlights at this luxurious hotel include a bar/lounge, a fitness center, and a garden. Fellow travelers love the helpful staff. Public transportation is just a short walk: Hommachi Station is steps away and Sakaisuji-hommachi Station is 9 minutes.