Me and my wife had a great week in Chicago, staying at the LondonHouse hotel.
Location is perfect, just a few steps from the Chicago River. And with this location you have so much within walking distance; Chicago Theatre, Millenium Park, Navy Pier, House of Blues et c et c
There are some really good restaurants in the area as well.
Room was really nice, with two King beds, and river view. Rooftop bar was busy (as we and everyone else wanted to enjoy the spring sun) and limited seating. For a relaxed drink maybe not the best, but good service in the bar and spectacular views